REVIEW ON LOSARTAN INDUCED HYPONATREMIA

  • S.Indhu Harini Assistant Professor, Koringa College of Pharmacy, Korangi
    subrahmanyamsatupati@gmail.com

Abstract

Hyponatremia is a frequently encountered electrolyte imbalance associated with significant morbidity and mortality. While diuretics, selective serotonin reuptake inhibitors (SSRIs), and anticonvulsants are well-recognized causes, angiotensin II receptor blockers (ARBs), particularly losartan, have also been implicated in rare cases. This review explores the potential mechanisms, clinical evidence, risk factors, diagnostic considerations, and management strategies related to losartan-induced hyponatremia. Awareness of this uncommon yet clinically significant adverse effect is essential for early recognition and prevention of complications.

Keywords: Hyponatremia, Losartan, Angiotensin II receptor blockers (ARBs), Electrolyte imbalance, Adverse drug reaction, Syndrome of inappropriate antidiuretic hormone secretion (SIADH)

References

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2. Mansukhbhai, H. J., Gupta, S., Sood, V. S., & Malhotra, S. D. (2019). Hyponatremia following losartan therapy in a patient with cerebrovascular attack: A case report. National Journal of Integrated Research in Medicine, 10(4), 83–85.
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S IH. REVIEW ON LOSARTAN INDUCED HYPONATREMIA. Am J Med Nat Sci [Internet]. 2026Jan.21 [cited 2026Mar.17];7(1):16-8. Available from: https://ajmns.com/index.php/journal/article/view/25
Issue
Volume-7, Issue-1, 2026
Section
Review Articles

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